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根据补丁研究,氨酸治疗诱导了年龄和性别相关的神经元活动变化

Tímea Májer1, Veronika Bódi1, Viktor Kelemen1

  • 1Department of Physiology and Neurobiology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.

Developmental neurobiology
|December 21, 2023
PubMed
概括

在发育过程中对大鼠进行的瓦尔酸治疗改变了神经元刺激能力,特别是在雌性中,这表明对自闭症谱系障碍模型的潜在影响. 这些变化可能涉及过极化激活的通道,并且随年龄而异.

关键词:
自闭症谱系障碍 自闭症谱系障碍大脑切片大脑切片电力生理学 电力生理学内皮层 (entorhinal cortex) 是一个内侧的皮层.是一种.前额叶皮层前额叶皮层.瓦尔酸为一种酸盐.整体细胞补丁紧.

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Patch Clamp

Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
In this method, a glass micropipette containing electrolyte solution is tightly sealed against a small portion of the cell membrane. As a result, a patch of the cell...
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