预后营养指数是Covid-19相关住院和死亡率的预测指标吗?
Muhammed Emin Demirkol1, Gulali Aktas1, Murat Alisik2
1Abant Izzet Baysal University, Department of Internal Medicine, Bolu, Turkey.
Malawi medical journal : the journal of Medical Association of Malawi
|December 21, 2023
概括
预后营养指数 (PNI) 可以预测COVID-19的结果. 患者的PNI水平较低表明住院和死亡风险较高,提醒医生潜在的严重程度.
科学领域:
- 医学研究 医学研究
- 炎症标志物的炎症标志物
- 在COVID-19的预后.
背景情况:
- 预后营养指数 (PNI) 是评估炎症和预测各种疾病结果的新兴标志物.
- COVID-19 给全球健康带来了重大挑战,需要可靠的预后工具.
研究的目的:
- 在门诊和住院COVID-19病例中调查预后营养指数 (PNI).
- 为了比较已故和幸存的COVID-19患者之间的PNI水平.
主要方法:
- 一项涉及4419名COVID-19患者 (2907名门诊患者,1512名住院患者) 的研究.
- 门诊和住院患者组之间的PNI水平的比较.
- 与死亡率相关的PNI分析 (已故患者与幸存患者).
主要成果:
- 住院患者的PNI (41.55) 显著低于门诊患者的PNI (51.95) (p<0.001).
- PNI ≤46.2预测的住院治疗需要,灵敏度为71.2%,特异性为83.5%.
- 已故患者的PNI (37) 低于幸存者 (50.45) (p<0.001).
- PNI ≤44.55预测死亡率,灵敏度为89.22%和特异性为78.87%.
结论:
- 对于COVID-19患者来说,PNI是一个有价值的预后指标.
- 降低PNI水平与COVID-19住院和死亡率增加的可能性有关.
- 医生应该考虑低PNI作为严重COVID-19结果的警告信号.
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