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Updated: Jul 7, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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Published on: September 18, 2014

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在患有牛皮关节炎的患者的外周血液中,I型干扰素通路和DNA损伤积累

George E Fragoulis1,2, Panagiotis A Ntouros1, Adrianos Nezos3

  • 1Joint Academic Rheumatology Program, First Department of Propaedeutic and Internal Medicine, National and Kapodistrian University of Athens Medical School, Athens, Greece.

Frontiers in immunology
|December 21, 2023
PubMed
概括

牛皮关节炎 (PsA) 显示DNA损伤增加,但没有预期的1型干扰素 (IFN-I) 途径激活. 这种意想不到的IFN-I下调可能在PsA发展中发挥作用,可能受到其他炎症类细胞因子的影响.

关键词:
造成的DNA损伤是DNA损伤.一个IL-1的IL-1.在IL-6的研究中,IL-6被认为是IL-6的基因.周边血液单核细胞 (PBMC) 是指周边血液单核细胞.牛皮关节炎 牛皮关节炎一种I型干扰素 干扰素

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