加拿大的侵入性肺炎球菌病监测,2020年
Alyssa Golden1, Averil Griffith1, Walter Demczuk1
1National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB.
概括
2020年加拿大侵入性肺炎球菌病 (IPD) 发病率下降. 然而,某些疫苗类型和非疫苗类型血清型的患病率以及多种药物耐药性增加,需要持续监测.
科学领域:
- 微生物学 微生物学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 侵入性肺炎球菌病 (IPD) 是加拿大的重大公共卫生问题.
- 虽然合疫苗已经减少了整体IPD发病率,但观察到血清型分布向非疫苗类型的转变.
- 本报告详细介绍了2020年加拿大的IPD人口统计,血清型和抗菌素耐药性.
研究的目的:
- 总结2020年加拿大IPD的流行病学特征.
- 分析血清型分布和IPD病例的趋势.
- 评估IPD分离物中的抗菌素耐药性模式.
主要方法:
- 2020年,从加拿大公共卫生实验室收集了IPD分离物的国家监测数据.
- 使用Quellung反应进行了血清型定.
- 确定了对抗菌素的敏感性,并使用加拿大报告疾病监测系统计算出发病率.
主要成果:
- 从2019年到2020年,所有年龄组的IPD总体发病率都下降了.
- 血清型4,3和8是最常见的整体.
- 趋势显示,从2016年到2020年,4,3,8和12F血清型的患病率在增加.
- PCV13血清型的患病率增加,多药耐药性IPD的患病率也增加.
结论:
- 尽管2020年IPD总体发病率下降,但特定血清型 (3,4,8,12F) 和多药性耐药性显示有所增加.
- 持续的国家监测对于监测IPD不断变化的血清型分布和抗菌素耐药性模式至关重要.
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