在肺癌查中手术切除良性结节:发生率和特征
John M Archer1, Dexter P Mendoza2, Yin P Hung3
1Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.
JTO clinical and research reports
|December 21, 2023
概括
手术切除被认为是癌症的良性肺结节是不常见的,但可能发生. 了解模仿癌症的良性结节可能有助于减少肺癌查 (LCS) 计划中不必要的手术.
科学领域:
- 肺部病理学 肺部病理学
- 胸部外科手术 胸部外科手术
- 放射学 放射学是一门学科.
背景情况:
- 肺癌查 (LCS) 经常识别需要干预的非恶性肺病变.
- 怀疑恶性瘤的良性结节的手术切除需要付出成本和潜在的并发症.
研究的目的:
- 为了评估在LCS计算机断层扫描 (CT) 中检测到的手术切除的良性肺结节的特征,这些结节被认为是恶性的.
主要方法:
- 在2014年6月至2021年1月期间接受LCS的4798名患者的回顾性分析.
- 从LCS注册表中识别和分析在假定癌症诊断下手术切除的良性肺结节.
- 评估患者的人口统计,成像特征和最终的病理诊断.
主要成果:
- 在4798名LCS患者中,148名 (3.1%) 的结节被切除;19名 (12.8%) 是良性的.
- 良性结节 (中等大小10毫米) 通常是固体 (78.9%),在上叶 (57.9%),并显示间隔增长 (76.5%) 或增加FDG吸收 (23.5%).
- 病理包括纤维化/痕 (n=8),颗粒状炎症 (n=3),良性瘤 (n=3);89.5%接受了亚叶切除.
结论:
- 在LCS期间手术切除良性结节,假定是恶性的,是罕见的.
- 良性和恶性结节之间重叠的成像特征使得一些不必要的手术不可避免.
- 了解模仿恶性瘤的良性病理可以帮助减少不必要的手术干预.
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