相关实验视频

Updated: Jul 7, 2025

CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery
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CRISPR Epigenome Editing in Human Cells using Plasmid DNA Transfection and mRNA Nucleofection Delivery

Published on: May 30, 2025

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通过向CRISPR-Cas12a系统的mRNA对核糖体框架转移进行可编程调制

Shih-Hong Huang1,2, Shih-Cheng Chen1,3, Tsu-Ying Wu4

  • 1Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

iScience
|December 21, 2023
PubMed
概括

克里斯普尔RNA和克里斯普尔-Cas12a增强了编程的核糖体框架转移 (-1 PRF),这是SARS-CoV-2复制中的一个关键过程. 该系统提供了一种针对病毒RNA和对抗未来的冠状病毒流行病的新策略.

关键词:
生物技术是生物技术.分子生物学分子生物学病毒学 病毒学

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