乌比基蛋白酶系统对前列腺癌中DNA损伤反应的影响 (评论)

Yan Lin1,2, Xiaofeng Jin1,2

  • 1Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Ningbo University, Ningbo, Zhejiang 315211, P.R. China.

概括

在DNA损伤反应 (DDR) 和全方位蛋白酶系统 (UPS) 中的缺陷通过引起基因组不稳定性来驱动癌症,特别是在前列腺癌 (PCa) 中. 针对这些途径为PCa生物标志物和疗法提供了潜力.

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