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周围B细胞水平预测了PD-1免疫治疗中晚期黑色素瘤患者的疗效和整体存活率

Xiaoli Liu1, Shuochuan Liu2, Zhiqiang Jiang3

  • 1Department of Integrated Traditional Chinese & Western Medicine, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, China.

Immunotherapy
|December 21, 2023
PubMed
概括

较低的外围B细胞计数与接受计划死亡-1 (PD-1) 阻断免疫治疗的晚期恶性黑色素瘤患者的更好的结果相关. 这一发现表明B细胞可以预测治疗反应和预后.

关键词:
B 细胞 B 细胞 B 细胞在PD-1中使用PD-1.生物标志物生物标志物免疫疗法 免疫疗法黑色素瘤是一种黑色素瘤.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.