在全甲状腺切除术后,术后缺甲状腺症 (POSH) 的发生率
Simon L Roberts1, Mahmoud El-Shikh1, Peyman Alam1
1Department of Oral and Maxillofacial Surgery, University Hospitals Sussex NHS Foundation Trust, St. Richard's Hospital, Spitalfield Ln, Chichester PO19 6SE, UK.
The British journal of oral & maxillofacial surgery
|December 21, 2023
概括
甲状腺切除术后的手术后缺甲状腺症 (POSH) 通常是短暂的,但恶性瘤诊断会增加风险. 一些患者经历了持续的低血症,需要长期管理.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 神经外科 神经外科
背景情况:
- 手术后缺甲状腺症 (POSH) 是完全甲状腺切除术后的一个常见并发症,导致低血症.
- 了解POSH的发生率和预测因素对于患者管理至关重要.
研究的目的:
- 为了确定全甲状腺切除术后POSH的发生率.
- 确定与POSH发展相关的外科手术预测因素.
主要方法:
- 对133名接受完全或完整甲状腺切除术的成年患者的回顾性分析.
- 评估POSH发生率,将其分类为短暂或长期POSH,并调查风险因素,包括性别,组织学和手术前甲状腺功能.
主要成果:
- 15%的人经历过渡性POSH,5%的人长期POSH (>6个月).
- 恶性瘤的组织学诊断是唯一重要的风险因素 (RR 2.95).
- 0.75%的人患有持续的POSH,3%的人表现出持续的边际低水平.
结论:
- 谨慎的外科手术技术将POSH发生率降至最低.
- 虽然大多数患者康复,但有些人需要长期补充,因为相对甲状腺功能不充分.
- 为了找到最佳的预防和治疗策略,需要进一步的研究.
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