麻症的预后和影响预后的因素
Bilge Bilgin1, Mehmet Kursat Bilgin2, Serhat Erol3
1Chest diseases. bilged6@gmail.com.
概括
麻症的预后往往是好的,58%的患者实现了缓解. 低疾病阶段和良好的肺功能等因素预测了有利的结果,而肺功能恶化表明预后不佳.
科学领域:
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
- 内部医学 内部医学
背景情况:
- 麻症是一种多系统性炎症性疾病,原因不明.
- 了解型硬化症的预后和影响因素对于患者管理至关重要.
- 这项研究旨在提供国家预后数据,并确定预后因素.
研究的目的:
- 为了确定土耳其的沙尔科病患者的预后.
- 为了确定与型硬化症预后相关的临床和功能因素.
主要方法:
- 对188名沙尔科发病患者的回顾性评估至少进行了三年 (2012-2017) 的跟踪.
- 通过增加放射学发现,功能障碍或治疗变化而定义的进展.
- 预后分为好 (缓解,稳定,回归) 和差 (进展,慢性,需要治疗的复发).
主要成果:
- 58%的患者有良好的预后,而42%的预后很差.
- 自发缓解发生在20.2%;肺高血压发生在10.6%;死亡率发生在4.25%.
- 良好的预后与低辐射阶段,高螺旋计/扩散能力,无症状状态和没有先前治疗有关. 进展与ACE/CRP增加和肺功能下降有关.
结论:
- 麻症的预后有所不同,很大一部分患者经历了良好的结果.
- 疾病的早期阶段,肺功能得到保护,缺乏症状是有利预后的关键指标.
- 监测肺功能和炎症标志物可以帮助预测沙尔科毒症的进展.
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