慢性咳中的治疗景观
1Division of Immunology, Immunity to Infection and Respiratory Medicine, University of Manchester and Manchester Academic Health Science Centre, Wythenshawe Hospital, Southmoor Road, Manchester, M23 9LT, UK. jacky.smith@manchester.ac.uk.
Lung
|December 21, 2023
概括
新的抗咳疗法正在出现,fefapixant最近在欧洲获得许可. 本综述涵盖了针对慢性咳疾病的现有未经许可的治疗方法和正在开发的新疗法.
科学领域:
- 药理学 药理学是指药理学的学科.
- 呼吸系统医学 呼吸系统医学
- 临床治疗学 临床治疗学
背景情况:
- 慢性咳是一个重大的临床挑战,有效治疗方法有限.
- 最近,新型抗咳疗法的开发加速了.
- 盖法皮克桑特是欧洲首个获得治疗慢性咳许可的新疗法.
研究的目的:
- 审查当前未经许可的慢性咳治疗方法.
- 详细介绍正在开发的耐火性慢性咳的治疗方法.
- 探索与异常性肺纤维化相关的咳的治疗选择和以前研究的化合物.
主要方法:
- 对抗咳疗法的文献综述.
- 对治疗慢性咳的许可药物和试验药物的分析.
- 对用于治疗咳的研究化合物的检查.
主要成果:
- 格法皮克桑 (Gefapixant) 是一种在欧洲新获得许可的抗咳疗法.
- 目前用于慢性咳的各种未经许可的治疗方法.
- 针对耐火性慢性咳和与异常性肺纤维化相关的咳,正在研究几个新型化合物.
结论:
- 慢性咳治疗的景观正在随着新的治疗选择而发展.
- 进一步的研究和开发对于管理耐火性慢性咳和相关疾病至关重要.
- 试验性疗法对具有有限治疗选择的患者来说是有前途的.
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