在Cestodes中发现新的腺体类型:神经分泌神经元释放到鱼主体中的秘密
N M Biserova1, I A Kutyrev2, V V Malakhov3
1Moscow State University, Moscow, Russia. nbiserova@yandex.ru.
概括
鱼类寄生虫中的神经分泌神经元 (NN) 释放影响宿主生理学的物质. 这些神经元充当内分泌腺和外分泌腺,对宿主血清做出反应.
科学领域:
- 寄生虫学的寄生虫学
- 神经内分泌学神经内分泌学
- 超结构生物学 超结构生物学
背景情况:
- 寄生虫有复杂的生理相互作用与宿主.
- 众所周知,神经分泌神经元 (NN) 调节各种生物体中的生理过程.
研究的目的:
- 为了研究鱼类寄生虫cestode plerocercoids的体内神经分泌神经元 (NNN) 的超结构和功能.
- 为了确定NNs在对宿主刺激的反应中的分泌活性.
主要方法:
- 超结构分析的plerocercoid体.
- 涉及宿主鱼血清暴露的实验操纵.
主要成果:
- 在五种鱼类寄生虫鱼物种的体中发现了NN的自由末端.
- 观察到NN可以将囊泡分泌到体膜表面和宿主体内.
- 在暴露于宿主鱼血清后,分泌率显著增加.
- 尼恩与前额腺体,肌体和肌肉形成对腺接触,作为内分泌腺体和外分泌腺体起作用.
结论:
- 鱼体内外围神经分泌神经元作为内分泌和外分泌腺体起作用.
- 这些NN分泌着影响宿主生理学的"操纵因素",其活性由宿主血清调节.
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