在密歇根州的布普伦诺芬处方在教育干预之后
Liying Chen1, Sheba Sethi2, Cara Poland3
1Department of Biostatistics, University of Michigan, Ann Arbor.
JAMA network open
|December 21, 2023
概括
密歇根阿片类药物协作 (MOC) 增加了布普伦诺芬处方者和阿片类药物使用障碍 (OUD) 治疗的患者. MOC参与与更多的临床医生处方布普伦诺芬和患者接受这种重要的OUD药物有关.
科学领域:
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
- 医疗保健服务研究 医疗服务研究
背景情况:
- 布普伦诺芬是阿片类药物使用障碍 (OUD) 治疗中未充分使用的药物,通常受到临床医生和社区障碍的限制.
- 密歇根阿片类药物协作 (MOC) 于2017年成立,旨在解决这些障碍并改善布诺啡的获取.
- MOC参与对布普伦诺芬治疗趋势的影响以前是未知的.
研究的目的:
- 确定MOC服务利用率与县级布普伦诺芬处方密度变化之间的关联.
- 评估接受布普伦诺芬治疗的患者MOC参与和时间趋势之间的关系.
主要方法:
- 一项队列研究设计,利用2015年5月至2020年8月在密歇根州各县分级实施MOC.
- 用线性固定效应回归的差异分析来评估MOC的整体影响.
- 用线性回归推断单个参与MOC的县的县特定结果.
主要成果:
- MOC参与与每10万人口中布普伦诺芬处方者的显著增加有关 (每月0.33,P=.002).
- 参与MOC的县份显示,每月接受布普伦诺芬的患者数量增加得更大 (每10万人口中有6.56人,P=.004).
- 到2020年,密歇根州83个县中有57个县 (68.7%) 已经使用MOC服务.
结论:
- 与密歇根阿片类药物协会的参与与布普伦诺芬处方者和患者的显著增加有关.
- MOC的外展和教育模式有效地增加了对阿片类药物使用障碍治疗的布普伦诺芬的获取.
- 这些发现凸显了MOC在克服一般医疗环境中布普伦诺芬治疗障碍方面的成功.
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