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硫酸盐类同类的溶酶体处理改变了向NKT细胞的特异性和癌症癌症中的免疫反应

Kumiko Nishio1, Lise Pasquet1, Kaddy Camara2

  • 1Vaccine Branch, Center for Cancer Research, National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA.

The Journal of clinical investigation
|December 21, 2023
PubMed
概括

树突细胞 (DC) 意外地对硫酸盐进行抗原处理,使其免疫细胞的特异性从II型转变为I型NKT细胞,增强了抗癌免疫力.

关键词:
处理抗原处理.细胞生物学 细胞生物学细胞免疫反应的细胞免疫反应.免疫学 免疫学 免疫学瘤抑制剂 瘤抑制剂

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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
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