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Updated: Jul 7, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

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通过直接维尼洛基的迈克尔-奥克萨-迈克尔序列对 thiazolopyran 衍生物进行酶选择性合成

Abhijit Manna1, Shweta Rohilla1, Vinod K Singh1

  • 1Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh 208 016, India.

Organic letters
|December 21, 2023
PubMed
概括

研究人员开发了一种新的催化方法,用于合成复杂的 thiazolopyran 衍生物. 这种高效的过程产生了具有四元立体中心的分子,在各种化学转换中非常有用.

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The attack of a nucleophile at the β carbon of an α,β-unsaturated carbonyl compound is called conjugate addition. Conjugate addition reactions of active methylene compounds, such as β-diketones, β-keto esters, β-keto nitriles, and α-nitro ketones, are called Michael addition reactions.
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