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Updated: Jul 7, 2025

Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA
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Single-Molecule Imaging of EWS-FLI1 Condensates Assembling on DNA

Published on: September 8, 2021

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行动中的转录启动的结构可视化

Xizi Chen1,2, Weida Liu1, Qianmin Wang1

  • 1Fudan University Shanghai Cancer Center, Institutes of Biomedical Sciences, New Cornerstone Science Laboratory, State Key Laboratory of Genetic Engineering, Department of Biochemistry and Biophysics, School of Life Sciences, Shanghai Key Laboratory of Radiation Oncology, and Shanghai Key Laboratory of Medical Epigenetics, Shanghai Medical College of Fudan University, Shanghai 200032, China.

Science (New York, N.Y.)
|December 21, 2023
PubMed
概括

这项研究揭示了RNA聚合酶II的转录启动的动态过程. 它表明一般转录因子 (GTF) 对于早期RNA合成至关重要,但必须脱离促进体逃逸.

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