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Updated: Jun 22, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
11:10

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

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通过估计HLA适应与贝叶斯概括的线性混合模型对HIV-1核受体使用的洞察力

Anna Hake1,2, Anja Germann3, Corena de Beer4,5

  • 1Research Group Computational Biology, Max Planck Institute for Informatics, Saarbrücken, Germany.

PLoS computational biology
|December 21, 2023
PubMed
概括

病毒对人类白细胞抗原 (HLA) 的适应影响人类免疫缺陷病毒I型 (HIV-1) 核心受体切换. 这项研究表明,HLA适应预测了HIV-1患者的核心受体使用和潜在开关.

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Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach07:06

Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach

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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

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相关概念视频

Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...