与Trichoderma中的非内细胞相比,内细胞基因组支持更大的代谢基因集群多样性
Kelsey Scott1, Zachary Konkel1,2, Emile Gluck-Thaler3
1Department of Plant Pathology, The Ohio State University, Columbus, OH, United States of America.
PloS one
|December 21, 2023
概括
内生菌Trichoderma真菌拥有扩大的基因库用于代谢物生产和真菌寄生虫,帮助它们的多功能生活方式. 基因组分析显示,生活方式的可塑性是关键,而不是特定的基因集群.
科学领域:
- 菌类基因组学 菌类基因组学
- 菌类学 菌类学是指菌类学.
- 进化生物学 进化生物学
背景情况:
- 体真菌表现出多样化的生活方式,包括内,菌和沙.
- 内生菌常常表现出比非内生菌更大的代谢基因库,但机制仍然不清楚.
- 特里科德玛的菌体内菌体患病率表明,有可能扩大基因库,使双重殖民成为可能.
研究的目的:
- 为了确定在内菌中过度代表的基因组特征.
- 了解真菌内性生活方式的基因组基础.
- 为了比较不同生活方式的Trichoderma物种中的代谢基因集群和真菌寄生虫基因.
主要方法:
- 38个Trichoderma基因组的比较基因组学,包括4个新测序的endophyticum分离物.
- 代谢基因集群多样性的分析.
- 评估真菌寄生虫基因含量,包括酸酶.
主要成果:
- 内生性Trichoderma基因组显示了总生物合成和降解基因集群的平均数量较高.
- 没有任何特定的代谢基因集群类独立地与内性生活方式联系在一起,在考虑了分化后.
- 几种真菌寄生虫基因,但不是基因酶,与内性Trichoderma基因组有关.
- 鉴定了一种藻类类基因集群的水平基因转移.
结论:
- 特里科德玛的基因组架构支持生活方式的可塑性,使其能够适应各种生态.
- 扩大的基因库有助于内性生活方式,促进代谢物生产和与其他生物体的相互作用.
- 内生植物在Trichoderma属内的二次新陈代谢多样化方面发挥着作用.
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