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连续107次DMEK手术的5年临床结果

Pierre Bichet¹, Rémi Moskwa¹, Christophe Goetz²

¹Ophthalmology Department, Mercy Hospital, Regional Hospital Center (CHR) of Metz-Thionville, Metz, France.

|December 21, 2023

概括

德塞米特膜内皮切层切层整形术 (DMEK) 提供了优秀的长期结果,移植的5年存活率为88%,并发症最小. 这项研究证实DMEK是安全有效的角膜移植选择.

科学领域:

眼科医生眼科眼科
角膜外科手术角膜外科手术
移植科学移植科学

背景情况:

德斯梅特膜内皮质角质整形 (DMEK) 是一种先进的内皮质角质整形技术.
需要进一步了解DMEK的长期临床结果,术后并发症和移植存活率.

研究的目的:

以追溯评估经DMEK后的长期临床结果,术后并发症和移植存活率.
将结果与现有的长期DMEK研究 (3-10年随访) 进行比较.

主要方法:

在2014-2018年间对107只接受DMEK治疗的眼睛进行了回顾性分析.
眼科检查在手术前进行,并在手术后长达5年的定期间隔进行.
卡普兰-梅尔5年移植存活分析;最佳校正视敏度 (BCVA),内皮细胞密度 (ECD) 和中角膜厚度 (CCT) 的评估.

主要成果:

累计5年移植存活率为88%;15个月内移植失败率为12%.
显著的BCVA改善 (0.6到0.05 logMAR) 持续长达5年.
观察到逐渐的ECD损失 (65%在5年内) 和CCT的减少.

结论:

DMEK显示出低的并发症率和高的移植存活期长达5年.
优秀和持续的临床结果支持DMEK的疗效.
DMEK是一种安全有效的长期治疗内皮角膜功能障碍的方法.

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