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Updated: Jul 7, 2025

Analysis of AtHIRD11 Intrinsic Disorder and Binding Towards Metal Ions by Capillary Gel Electrophoresis and Affinity Capillary Electrophoresis
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Analysis of AtHIRD11 Intrinsic Disorder and Binding Towards Metal Ions by Capillary Gel Electrophoresis and Affinity Capillary Electrophoresis

Published on: August 22, 2018

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热稳定性和结合亲和力的关系在金属结合的WW-域微受体中

Truc Lam Pham1, Marcos R Conde González1,2, Sunnatullo Fazliev1,2,3

  • 1Institute of Organic Chemistry, Heidelberg University, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany.

Chembiochem : a European journal of chemical biology
|December 21, 2023
PubMed
概括

设计稳定的金属微蛋白可以提高金属结合亲和力. 经过重新设计的WW域变体显示出更好的热稳定性,导致Ni (II),Zn (II) 和Cu (II) 等双价金属的结合明显更强.

关键词:
在WWW域名 WW域名.金属结合的金属绑定迷你蛋白质微型蛋白质蛋白质工程工程 蛋白质工程这是一种β-叶片.

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