研究COVID以加强恢复 (RECOVER) 怀孕研究:理由,目标和设计
Torri D Metz1, Rebecca G Clifton2, Richard Gallagher3
1Department of Obstetrics and Gynecology, University of Utah Health Hospitals and Clinics, Salt Lake City, UT, United States of America.
这项研究调查了孕妇及其子女的长期COVID风险. 它旨在了解怀孕期间的SARS-CoV-2感染如何影响孕产妇的急性后遗症和后代的健康结果.
科学领域:
- 生殖健康 生殖健康
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 怀孕会改变免疫反应,可能会影响对SARS-CoV-2 (PASC) 或长期COVID的急性后续病变的易感性.
- 评估暴露于子宫内SARS-CoV-2的儿童的长期健康结果至关重要.
研究的目的:
- 评估怀孕期间的SARS-CoV-2感染是否会改变PASC风险因素,流行率和表型.
- 要确定在子宫内对SARS-CoV-2的暴露是否会增加儿童长期不良健康结果的风险.
主要方法:
- 恢复怀孕队列是一个结合前性和后性研究,招募了2300名怀孕者及其后代.
- 参与者从27个临床场所和远程招募,包括怀孕期间感染或没有感染SARS-CoV-2的个人.
- 后代在多个年龄段接受神经发育和健康结果查,并收集血液进行抗体检测.
主要成果:
- 这项研究正在进行中,结果正在等待.
- 这项研究旨在在怀孕期间感染SARS-CoV-2后提供关于母亲和儿童健康的关键数据.
结论:
- 恢复怀孕将澄清妊娠期SARS-CoV-2感染对母亲PASC的影响.
- 这项研究将确定在子宫内暴露于SARS-CoV-2的儿童的长期健康轨迹.
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