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Updated: Jul 7, 2025

Biotinylated Cell-penetrating Peptides to Study Intracellular Protein-protein Interactions
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Published on: December 20, 2017

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ATXN2是N端蛋白解的目标

Monika Chitre1,2, Patrick Emery1,2

  • 1Department of Neurobiology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America.

PloS one
|December 21, 2023
PubMed
概括

脊髓小脑动症2 (SCA2) 涉及到Ataxin-2 (ATXN2) 蛋白质碎片. 这项研究表明,ATXN2经历N端裂变,释放聚胺 (polyQ) 片段,可能导致SCA2病理.

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