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Updated: Jul 7, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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利用p53改善肺癌治疗的免疫疗法

Xiaoteng Niu1, Luis Martinez2

  • 1Department of Pathology, Stony Brook University, Stony Brook, New York.

Cancer research
|December 21, 2023
PubMed
概括

p53突变和瘤异质性可能导致肺癌对免疫检查点阻塞 (ICB) 治疗产生抵抗力,即使瘤突变负担 (TMB) 高. 将ICB与STING激动剂或p53诱导剂结合使用可能会提高治疗疗效.

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