急性髓性白血病:当前的理解和管理
Michelle Becker1, Kyle A Farina, John Mascarenhas
1Michelle Becker practices in the adult leukemia program at the Icahn School of Medicine at Mount Sinai in New York, N.Y. Kyle A. Farina is a clinical pharmacy manager, working on the leukemia service at Mount Sinai Hospital in New York, N.Y. John Mascarenhas is director of the adult leukemia program, leader of the Myeloproliferative Disorders Clinical Research Program in the Division of Hematology/Oncology at the Tisch Cancer Institute at Mount Sinai Hospital, and a professor of medicine at the Icahn School of Medicine at Mount Sinai. Dr. Farina discloses that he is a consultant and speaker for Bristol Myers Squibb. Dr. Mascarenhas discloses that he is a consultant for Celgene Corp., Bristol Myers Squibb Co., Incyte Inc., F. Hoffmann-La Roche AG, PharmaEssentia Corp., Geron Corp., CTI Biopharma Corp., MorphoSys AG, Abbvie Inc., Kartos Therapeutics, Novartis AG, Sierra Oncology Inc., GSK plc, Karyopharm Therapeutics Inc., Galecto Inc., Imago BioSciences Inc., and Pfizer Inc., and receives research funding from Bristol Myers Squibb, Abbvie, CTI Biopharma, Incyte, Merck & Co., Novartis, Roche, Kartos, PharmaEssentia, and Geron. The authors have disclosed no other potential conflicts of interest, financial or otherwise.
急性髓性白血病 (AML) 是最常见的成人急性白血病,需要及时治疗才能生存. 准确的分类和全面的支持性护理对于管理这种侵袭性癌症至关重要.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 急性髓性白血病 (AML) 是成年人患急性白血病的主要类型,其特征是预后不佳.
- 及时干预对于改善AML患者的治疗结果至关重要.
研究的目的:
- 提供关于急性髓性白血病 (AML) 的全面概述.
- 讨论当前的治疗策略和AML患者的支持性护理.
主要方法:
- 审查目前的文献和AML诊断和管理的临床指南.
- 世界卫生组织 (WHO) 对AML预后的分类标准的讨论.
主要成果:
- 通过世卫组织标准对AML进行分类,以指导风险适应治疗.
- 在化疗期间,包括输血和抗菌药物治疗在内的支持性护理至关重要.
结论:
- 对所有临床医生来说,早期识别AML症状至关重要.
- 患者需要血液学家/瘤学家的专业护理,以获得最佳的管理.
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