大麻使用障碍和入住重症监护的结果:一个追溯的多中心队列研究

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Laura Renger¹, Jayesh Dhanani², Elissa Milford²

¹Department of Intensive Care Services, Royal Brisbane and Womens Hospital, Brisbane, Queensland, Australia.

Journal of critical care

|December 21, 2023

概括

大麻素使用障碍影响了0.8%的重症监护室 (ICU) 住院患者,导致ICU停留时间更长. 虽然最初的生存率更好,但在调整患者因素后,这种效应消失了.

科学领域:

关键护理医学关键护理医学
成精神病学成精神病学
公共卫生公共卫生

背景情况:

在全球范围内,大麻素使用障碍 (CUD) 越来越普遍.
了解CUD对严重疾病结果的影响对于患者管理至关重要.
关于入住重症监护病房 (ICU) 的CUD患者的特征和结果的数据有限.

研究的目的:

为了确定大麻素使用障碍在ICU患者中的患病率.
在这个人群中确定与CUD相关的因素.
评估CUD对ICU停留时间和生存时间的影响.

主要方法:

在澳大利亚四个公共ICU进行了队列研究.
患有与大麻素有关的精神和行为障碍的患者使用ICD-10-AM代码进行识别.
分析了人口统计数据,并发症,疾病严重程度,ICU停留时间 (LOS) 和90天死亡率.

主要成果:

在34,680例ICU入院患者中,0.8%的患者被诊断出使用大麻素的障碍.
患有CUD的患者年轻,更可能是男性,并患有较少的并发症和较低的疾病严重程度.
对于患有CUD的患者来说,ICU LOS显著更长 (2 vs. 1天),但90天病例死亡率较低 (6% vs. 10%).
经过对混因素进行调整后,CUD的生存益处并不显著.

结论:

大麻素使用障碍占ICU入院的比例很小,但很大.
CUD与更长的ICU停留时间有关.
需要进一步的研究来阐明大麻素在严重疾病中的作用及其长期影响.

关键词:

大麻素是一种大麻素.大麻大麻大麻大麻大麻大麻大麻关键的护理关键的护理重症监护室的重症监护室是重症监护室的重症监护室.大麻大麻是一种大麻.

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