线粒体化物脱酶-2协调硫化 - AMPK轴以减轻高葡萄糖诱导的胰腺β细胞功能障碍,由谷氨抗氧化剂系统

Udayakumar Karunakaran1, Suma Elumalai1, Seung Min Chung2

  • 1Innovative Center for Aging Research, Yeungnam University Medical Center, Daegu, Republic of Korea.

Redox biology
|December 21, 2023
PubMed
概括

持续的高血糖导致糖尿病中的β细胞丧失. 激活线粒体化物脱酶-2 (ALDH2) 通过增强抗氧化防御和关键信号通路来保护β细胞.

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