基于ATN分类系统的近视性黄斑病变的进展
Rongrong Zhang1, Jiarui Xue2, Minmin Zheng2
1Department of Ophthalmology, Fuyang People's Hospital of Anhui Medical University, Fuyang, China, 1305551241@qq.com.
概括
近视性黄斑病 (MM) 的进展与年龄较大,轴线长度较长 (AL) 和特定的眼部特征有关. 超过5.15毫米的圆盘-椎间盘距离 (DFD) 是MM进展的重要预测因素.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 视网膜疾病 视网膜疾病
背景情况:
- 近视性黄斑病 (MM) 是不可逆转的视力障碍和中央视力丧失的主要原因.
- 了解MM进展的风险因素对于及时干预和管理至关重要.
研究的目的:
- 使用ATN分类系统评估与近视性黄斑病变 (MM) 的进展相关的风险因素.
- 确定特定的眼睛参数,预测高近视患者的MM进展.
主要方法:
- 对69名高近视患者 (年龄大于40岁) 的临床数据的回顾性分析,随访时间超过2年.
- 用 fundus 摄影和 OCT 检查来评估 ATN 分类的变化.
- 分析的因素包括轴长 (AL),球形等效 (SE),底状厚度 (SFCT),光盘-状距离 (DFD),光盘倾斜和副状缩 (PPA).
主要成果:
- 在研究队列中,MM进展率约为25.56%.
- 在基线时,延长的DFD和更薄的SFCT与MM进展有显著的关联.
- 确定DFD是一个实质性的危险风险因素 (调整后OR=1.672),预测进展的切断值为5.15毫米 (AUC:0.794).
- 进展组显示年龄较大,AL较长,光盘倾斜度较高,在基线时有更多的先前存在的PPA.
结论:
- MM的进展与年龄较大,较长的AL,高盘倾斜,先前存在的PPA,较薄的SFCT和较长的DFD有关.
- DFD是MM进展的关键预测因素,长度>5.15毫米表明风险更高.
- ATN分类系统有助于识别高近视的进展风险因素.
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