中心敏感化:在初级全膝关节整形术后,心理痛苦和糟糕的结果之间缺失的联系
J Ryan Martin1, Rogelio A Coronado1, Jacob M Wilson1
1Department of Orthopedics, Vanderbilt University Medical Center, Nashville, Tennessee.
The Journal of arthroplasty
|December 21, 2023
概括
手术前的心理困扰和疼痛处理变化确定了不同的全膝关节整形术 (TKA) 患者子组. 中心敏感性,而不仅仅是痛苦,预测了TKA的不良结果和更高的阿片类药物使用.
科学领域:
- 整形外科手术 整形外科手术
- 治疗疼痛的药物 治疗疼痛的药物
- 心理医学是一种心理医学.
背景情况:
- 手术前的心理痛苦是全膝关节整形术 (TKA) 后不良结果的已知预测因素.
- 然而,单单是心理痛苦可能是一个太普遍的预测因素.
- 基于心理状态和疼痛处理的不同患者子组可能会提供更好的风险分层.
研究的目的:
- 根据心理状态和改变的疼痛处理来确定不同的手术前TKA患者子组.
- 确定这些子组是否预测TKA后的不良临床结果.
主要方法:
- 112名TKA患者接受了心理状态 (抑郁,焦虑,灾难化) 和疼痛处理 (外围和中心敏感化) 的手术前评估.
- 使用定量感官测试来评估疼痛敏感性.
- 集群分析确定了患者子组,结果 (疼痛,功能,阿片类药物使用) 在TKA后6周和6个月前性评估.
主要成果:
- 确定了三个不同的手术前TKA患者亚组:低风险 (LR),高风险的集中疼痛和高风险的外围疼痛.
- 与LR患者相比,高风险集中疼痛患者在6个月后表现出明显更差的功能和更多的阿片类药物使用.
- 高风险的外围疼痛患者在6个月后的结果与LR患者相似.
结论:
- 在患有心理并发症的TKA患者中,中心敏感化是与功能不良结果和增加阿片类药物使用的风险增加相关的关键因素.
- 中心敏感化可能会弥合心理因素和不利的TKA结果.
- 在手术前对中心敏感性的评估可以改善TKA患者的心理社会风险因素的风险分层.
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