非麻醉医生使用目标控制输液在常规消化道内镜中给药的propofol的安全性和耐受性结果
Francesco Vito Mandarino1, Lorella Fanti1, Alberto Barchi1
1Department of Gastroenterology and Gastrointestinal Endosco, Vita-Salute San Raffaele University, Scientific Institute San Raffaele, Milan, Italy.
Gastrointestinal endoscopy
|December 21, 2023
概括
使用目标控制输注 (TCI) 的非麻醉学家给药的普罗波 (NAAP) 是安全有效的内镜. 这种方法确保了最佳的普罗波福尔剂量,导致高患者满意度和最小的不良事件.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 非麻醉师管理的普罗波 (NAAP) 越来越多地用于镇静.
- 在临床实践中,NAAP的目标控制输注 (TCI) 数据有限.
- 基于患者参数,TCI优化了药物输送,以提高安全性和舒适性.
研究的目的:
- 使用TCI评估与NAAP相关的不良事件 (AE) 的发生率.
- 为了评估患者对通过TCI管理的NAAP的满意度.
- 在大型程序队列中分析NAAP-TCI的安全性和有效性.
主要方法:
- 对18,302例门诊肠道内镜手术的回顾性队列研究.
- 包括接受EGD和结肠镜检查的低风险患者 (ASA分数I-II).
- 在2019年5月至2021年11月期间,单个学术医疗中心的连续入学.
主要成果:
- 总共分析了18302个手术 (7162个EGD,11140个结肠镜).
- 在1.3%的手术中发生了不良事件,EGD和结肠镜之间没有显著差异.
- 患者的满意度很高,98.9%的人愿意重复手术;年龄是与AEs相关的唯一独立因素.
结论:
- 使用TCI的NAAP是常规内镜手术的安全有效镇静策略.
- 个性化的普罗波福尔剂量和熟练的操作员的存在是成功的NAAP镇静管理的关键.
- 这项研究支持NAAP-TCI的广泛采用,以提高患者的舒适性和程序安全性.
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