蛇咬伤受害者的急救和医院前实践:持续使用有害干预措施
Kalana Maduwage1, Sujani Kodagoda Gamage2, José María Gutiérrez3
1Discipline of Biomedical Sciences, University of New England, NSW, 2350, Australia.
Toxicon : official journal of the International Society on Toxinology
|December 21, 2023
概括
蛇中毒 (SBE) 的急救和医院前 (FAPH) 实践在全球广泛. 虽然带是最常见的,但许多有害的FAPH干预仍然存在,需要特定的环境规避计划.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 蛇毒 (SBE) 是一个重要的全球健康问题.
- 世界各地的患者和社区经常使用急救和医院前干预 (FAPH).
- 许多传统的FAPH实践的有效性和安全性仍然未经验证.
研究的目的:
- 对全球SBE病例中使用的FAPH实践的文献进行审查和分析.
- 确定最常见的FAPH干预措施及其地理分布.
- 突出潜在的有害做法,并为未来的公共卫生战略提供信息.
主要方法:
- 1947年至2023年间发表的前性研究的系统文献综述.
- 包含符合预先定义的标准的71个出版物.
- 对FAPH干预频率和地理差异的分析.
主要成果:
- 带是最常见的FAPH干预措施 (45.8%),在亚洲应用最高 (55.7%).
- 其他常见做法包括洗伤 (9.1%),切割/切口 (6.7%),局部应用 (5.6%) 和草药 (2.9%).
- 观察到FAPH实践的地理差异,干预频率没有显著的时间趋势.
结论:
- 对于SBE,FAPH的干预措施被广泛使用,包括潜在的有害做法.
- 需要进行更多的地理细节化和社区调查的进一步研究.
- 制定和推广当地定制的计划,以阻止有害的FAPH做法,并评估干预的有效性至关重要.
相关概念视频
Prevention of Further Absorption of Poison
825
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
825
Antidotes
649
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
649
Anticholinesterase Agents: Poisoning and Treatment
869
Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is...
869
Methods of reducing fever
666
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:
666
Endotracheal Intubation II: Nursing Management
684
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
684
Enhanced Elimination of Poison
518
Poison can be effectively removed from the gastrointestinal (GI) tract through various decontamination procedures.
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
518


