视觉刺激调节局域潜力,但在人类听觉皮层中没有高频活动
Jyrki Ahveninen1,2, Hsin-Ju Lee3,4, Hsiang-Yu Yu5,6
1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129 jahveninen@mgh.harvard.edu.
概括
视觉刺激可以影响听觉皮层 (ACs),但内记录显示这是调制,而不是积极的视觉处理. 宽带高频活动是神经元发射的标志物,在AC中视觉输入并没有增加.
科学领域:
- 神经科学是一个神经科学.
- 听觉感知是一种听觉感知.
- 感官整合 感官整合
背景情况:
- 神经成像表明视觉输入影响人类听觉皮层 (ACs).
- 目前仍有争议,这是否反映了积极的视觉处理,还是仅仅是对听觉处理的调制.
- 宽带高频活动 (BHFA) 是神经元激发的潜在标志物.
研究的目的:
- 为了调查视觉刺激是否引起人类ACs的积极视觉处理.
- 通过视觉刺激来区分主动处理和听觉功能的调制.
- 检查BHFA在AC中交叉感官影响中的作用.
主要方法:
- 在16名参与者中使用立体EEG深度电极,靠近交流电源.
- 呈现了听觉,视觉和视听刺激.
- 使用反向建模分析了内事件相关潜力 (iERPs) 和宽带高频活动 (BHFA).
主要成果:
- 在AC中观察到对视觉刺激的交叉感官反应,滞后于听觉反应.
- 视觉刺激调节了低频振荡,并触发了与事件相关的脱同步.
- 重要的是,在视觉刺激后,AC中的BHFA并没有显著增加,即使在视听条件下也是如此.
结论:
- 内录音证实了人类AC中视觉刺激对听觉处理的交叉感官调制.
- 证据不支持ACs中的积极视觉处理.
- 对交流的视觉影响似乎是调制性的,而不是由视觉神经元发射驱动的.
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