为非工程师设计一个电离源的原型
Kevan T Knizner1, Seth M Eisenberg1, David C Muddiman1
1FTMS Laboratory for Human Health Research, Department of Chemistry, North Carolina State University, Raleigh, NC, 27695, USA.
Journal of mass spectrometry : JMS
|December 21, 2023
概括
本教程展示了如何使用现代工具对新型质谱仪器 (MS) 进行原型设计,表明不需要工程学位. 它涵盖了原型设计过程,技能和常见的硬件/软件,用于开发新的MS分析平台.
科学领域:
- 分析化学 分析化学
- 生物技术仪器仪器仪表 生物技术仪器仪表
背景情况:
- 新型质谱 (MS) 平台增强了生物和环境样本中的分子检测和量化.
- 商用MS仪器的开发在很大程度上依赖于最初的原型创新.
- 生物技术公司推动新MS仪器的研发,从可访问的原型工具中受益.
研究的目的:
- 为科学家和工程师提供关于仪器原型设计的教程.
- 证明工程学学位对于设计和制造原型MS仪器并不必不可少.
- 突出用于仪器原型的现代硬件和软件的可访问性.
主要方法:
- 案例研究:开发下一代IR-MALDESI的发展.
- 讨论仪器原型制造过程中的基本步骤.
- 在初始仪器原型中使用的常见硬件和软件的概述.
主要成果:
- 现代硬件和软件显著简化了原型MS仪器仪表的过程.
- 下一代IR-MALDESI源的开发是成功的原型设计的实际例子.
- 确定了有效原型设计的关键技能和资源.
结论:
- 使用当前的工具,为更广泛的科学受众实现了新型MS仪器的原型设计.
- 可访问的原型设计为基于MS的分析平台提供了进一步的创新.
- 这项工作降低了开发下一代MS仪器的进入壁垒.
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