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Updated: Jul 7, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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斯克瓦拉米德通过降低细胞内来增强NLRP3炎症酶激活

Paula I Seoane1,2,3, James A Beswick4,5, Andrew G Leach4

  • 1Division of Neuroscience, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK. paula.seoanedenicola@manchester.ac.uk.

Cell death discovery
|December 21, 2023
PubMed
概括

对称的二甲胺增强了NLRP3炎症酶的激活,通过促进离子 (K+) 流动. 这些化合物为需要增加NLRP3活性的疾病提供了潜在的治疗策略.

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