牛皮关节炎患者的睡眠质量及其与疾病活动和并发症的关系:一个横截面研究
Esther Toledano1, Cristina Hidalgo2, Luis Gómez-Lechón3
1Rheumatology Department, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Scientific reports
|December 21, 2023
概括
睡眠质量差影响了超过60%的牛皮关节炎患者,疲劳和情绪因素显著影响睡眠,而不是炎症. 这凸显了整体患者护理的必要性.
科学领域:
- 类风湿病学 类风湿病学
- 睡眠医学 睡眠医学
- 精神病体医学是一种精神病体医学.
背景情况:
- 牛皮关节炎 (PsA) 的评估是复杂的,越来越多地结合了患者报告的结果.
- 关于PSA睡眠质量的先前研究受到小样本大小和未能考虑炎症和心理因素的限制.
- 与轴心PSA和睡眠药物使用相关的睡眠质量数据很少.
研究的目的:
- 为了评估一组牛皮关节炎患者的睡眠质量.
- 研究睡眠质量与临床特征,疾病活动 (外围和轴向),功能,疾病影响,疲劳和心理状态之间的关系.
- 确定影响PsA睡眠质量的关键因素.
主要方法:
- 一项涉及连续247名牛皮关节炎患者的横截面研究.
- 使用匹兹堡睡眠质量指数 (PSQI) 评估睡眠质量.
- 分析了与各种疾病活动指数,功能评估,影响问卷和心理尺度 (焦虑,抑郁,疲劳) 的相关性. 构建了一个多重线性回归模型.
主要成果:
- 近三分之二 (63.15%) 的患者报告睡眠质量不佳.
- 较差的睡眠质量与女性性别,较高的关节数量,增加的外周和轴向疾病活动,疲劳,焦虑,抑郁,功能不佳和更大的疾病影响有显著联系.
- 多重线性回归确定疼痛和疲劳是睡眠质量模型的重要贡献者 (40%),疲劳是更强的预测因素.
结论:
- 睡眠质量差在牛皮关节炎患者中非常普遍.
- 情绪因素,特别是疲劳和焦虑,似乎比PsA的炎症标志物更能影响睡眠质量.
- 研究结果强调了在治疗牛皮关节炎中睡眠障碍时,应对心理健康和疲劳的重要性.
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