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损坏的FADD/BID信号传递调解了多发性骨髓瘤中免疫治疗的交叉耐药性

Umair Munawar1, Xiang Zhou1, Sabrina Prommersberger1

  • 1Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.

Communications biology
|December 22, 2023
PubMed
概括

死亡受体信号受损是多发性骨髓瘤 (MM) 中对T细胞免疫疗法的新抵抗机制. 这种涉及FADD/BID的途径对于治疗反应至关重要,为MM提供了新的治疗点.

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