生物标记方法用于动物识别,使用可溶解的微针阵列,由可定制模具制成
1Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-Ku, Tokyo, 153-8505, Japan.
Scientific reports
|December 22, 2023
概括
这项研究引入了一种新的微针阵列补丁 (MAP) 用于最小侵入性动物识别. 生物标记方法使用可溶解的微针来提供皮肤染料,提供持久且易于阅读的识别系统.
科学领域:
- 生物技术是生物技术.
- 动物科学动物科学
- 材料科学 材料科学 材料科学
背景情况:
- 有效的动物识别对于人类和动物的共存和管理至关重要.
- 传统的方法如耳孔,纹身和射频芯片都有局限性,包括侵入性和依赖外部设备.
- 需要先进的,最少侵入性的动物识别技术.
研究的目的:
- 开发和评估一种新的生物标记方法,使用可溶性微针阵列补丁 (MAP) 来识别动物.
- 创建一个可定制MAP的制造工艺,能够将图案染料输入皮肤.
- 评估动物模型中图案生物标记的可行性,耐用性和可读性.
主要方法:
- 制造定制的女性模具,用于创建有图案的微针阵列补丁 (MAP).
- 使用可溶解的微针阵列,将染料直接送入皮肤层进行生物标记.
- 进行基本评估和动物实验 (老鼠模型),以测试MAP的特性和性能.
- 评估形成的皮肤图案的长期可读性和耐用性.
主要成果:
- 成功制造具有可定制字符和数字的图案MAP.
- 在小鼠皮肤上使用开发的MAPs证明了微创生物标记的可行性.
- 确认生物标记在一个多月内保持清晰可读.
- 该方法允许直接将各种标签输送到皮肤层.
结论:
- 拟议的微针阵列补丁 (MAP) 生物标记方法为动物识别提供了一种最小侵入性和有效的方法.
- 这种技术消除了与传统方法相关的外部设备和复杂程序的需求.
- 开发的技术有潜在的应用在未来嵌入各种标签在动物和人类的皮肤.
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