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埃塞俄比亚亚的斯亚贝巴儿童癌症的发生率和模式 (2012-2017)
Amanuel Belay1, Ahmed Ali2, Wondimu Ayele2
1Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT- Africa), Addis Ababa University, Addis Ababa, Ethiopia. amanbelays@gmail.com.
BMC cancer
|December 22, 2023
概括
亚的斯亚贝巴的儿童癌症发病率很高,白血病是最常见的类型. 男孩的发病率更高,并且随着年龄的增长而增加,但从2012年到2017年,总体发病率下降.
科学领域:
- 儿科瘤学 儿科瘤学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 儿童癌症是一个日益严重的全球健康问题,也是发达国家儿童死亡的主要原因.
- 埃塞俄比亚儿童癌症的流行病学数据仍然有限.
- 这项研究通过检查亚的斯亚贝巴的儿童癌症发病率来解决知识差距.
研究的目的:
- 评估亚的斯亚贝巴的儿童癌症发病率模式.
- 为公共卫生规划和干预提供关键的流行病学数据.
- 为未来的儿童癌症研究在埃塞俄比亚建立基线数据.
主要方法:
- 利用了亚的斯亚贝巴市基于人口的癌症登记处的数据,用于2012年至2017年间在0-14岁儿童中诊断的侵入性癌症病例.
- 根据国际儿童癌症分类第三版 (ICCC-3) 根据形态学和主要部位分类的癌症病例.
- 使用直接方法与世界标准人口计算年龄标准化发病率 (ASR).
主要成果:
- 儿童癌症的平均年发病率为每百万例84.6例,男孩 (98.97/百万) 比女孩 (69.7/百万) 高.
- 发病率随着年龄的增长而增加,从7080万 (0-4岁) 增加到110万 (10-14岁).
- 白血病是最常见的癌症 (29.1%的男孩,26.8%的女孩),其次是淋巴瘤和脏瘤. 总体发病率从2012年的87.02/百万下降到2017年的51.07/百万.
结论:
- 在亚的斯亚贝巴,儿童癌症对公共卫生造成了重大负担.
- 在亚的斯亚贝巴观察到的癌症分布模式与非洲其他地区的不同.
- 进一步的研究是必要的,以了解癌症模式的区域差异,并确定风险因素.
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