相关实验视频

Updated: Jul 7, 2025

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

广场光学连贯断层扫描血管图的诊断性能,用于检测高近视的开角玻璃眼

Yinhang Zhang¹, Deming Wang¹, Fengbin Lin¹

¹State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.

Acta ophthalmologica

|December 22, 2023

概括

视网膜中部1-6毫米区域的毛细血管密度 (CD) 是检测高近视性开角青光眼 (HM-OAG) 的更好的指标,而不是外围区域. 外围扫描对HM-OAG检测没有额外的诊断价值.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
玻璃眼研究研究玻璃眼研究

背景情况:

高近视 (HM) 对于诊断开放角眼 (OAG) 提出了独特的挑战.
使用光连贯断层扫描血管学 (OCTA) 评估毛细管网络变化是一种有前途的诊断方法.
界定特定的视网膜区域以实现最佳诊断性能至关重要.

研究的目的:

为了比较毛细血管密度 (CD) 在中央 (1-6mm) 与外围 (6-12mm) 视网膜环状区域的诊断效果,用于检测高度近视的开角青光眼 (HM-OAG).
在这种情况下,评估广场扫描源光学连贯性断层扫描血管学 (WF SS-OCTA) 的实用性.

主要方法:

招募了206只眼睛与HM和103只眼睛与HM-OAG.
获取的WF SS-OCTA图像集中在焦点上.
使用内置软件在1-3mm,3-6mm,6-9mm和9-12mm环状区域测量了表面毛细管 (SCP) CD.
使用接收器操作特征曲线 (AUROC) 下面的面积来比较诊断性能.

主要成果:

中部1-6mm区域在HM-OAG检测方面表现出优越的诊断性能 (AUROC=0.849) 与外围6-12mm区域 (AUROC=0.756,p=0.001) 相比.
SCP CD AUROCs在3-6mm区域达到峰值 (AUROC=0.858),并在更大的直径下降.
3-6mm区域的下方象限显示了最高的诊断性能 (AUROC=0.859).

结论:

中央视网膜毛细血管密度 (1-6mm) 在诊断高度近视眼中检测HM-OAG时在诊断上优越.
评估外围视网膜区域 (6-12mm) 在这个人群中对HM-OAG没有额外的诊断益处.
WF SS-OCTA是评估HM-OAG中微血管变化的宝贵工具.

关键词:

毛细血管的密度密度诊断性表现的诊断性表现是什么高近视的高近视是一个问题.开放角格劳科马 (Open-Angle Glaucoma) 是一种眼睛上的光.光学连贯性断层扫描血管图谱广场广场的广场是一个广场的广场.

更多相关视频

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

相关概念视频

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...