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在COVID-19之后,生活质量和运作的认知和情感预测因素
Mar Ariza1,2, Neus Cano1,3, Bàrbara Segura2,4,5
1Grup de Recerca en Cervell, Cognició i Conducta, Consorci Sanitari de Terrassa (CST), Terrassa, Spain.
Annals of clinical and translational neurology
|December 22, 2023
概括
长期COVID严重影响与健康相关的生活质量 (HRQoL) 和日常功能. 降低HRQoL和功能的关键预测因素包括后COVID患者的抑郁症状,疲劳和较慢的心理处理速度.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 心理学 心理学 心理学
背景情况:
- 在2019年冠状病毒病 (COVID-19) 后持续的症状可能导致与健康相关的生活质量 (HRQoL) 的长期下降.
- 认知和情绪因素是HRQoL的关键决定因素,但在COVID后患有持续症状的患者中,它们的预后意义需要进一步调查.
研究的目的:
- 描述生活质量 (QoL),HRQoL,以及在不同程度的COVID-19中经历COVID后症状的个体中的功能.
- 调查认知和情绪变量的 QoL,HRQoL 和 COVID 后人口的整体功能预测价值.
主要方法:
- 在492名参与者 (398名COVID后,124名对照) 上进行了神经行为检查,评估认知,情绪,QoL/HRQoL (WHOQOL-BREF,EQ-5D) 和功能 (WHODAS-II).
- 统计分析包括对协差和线性回归模型的分析,以比较组,并确定QoL和功能预测因素.
主要成果:
- 与健康对照组相比,COVID后的组表现出明显较低的QOL,HRQoL和功能.
- 回归模型确定了抑郁症状,后COVID症状,就业状况,收入和心理处理速度作为QoL和功能显著预测因素,解释了大量的差异 (17%-60.2%).
- 疲劳,抑郁症状和心理处理速度减慢被确定为WHODAS功能得分下降的主要预测因素.
结论:
- 与未受影响个体相比,在COVID-19后出现持续症状的个体体验到降低了QoL/HRQoL和功能障碍.
- 抑郁症状,疲劳和认知障碍,特别是较慢的心理处理速度,是长期COVID人口中较差的QoL/HRQoL和功能结果的显著预测因素.
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