乳制品和质在多发性硬化症的疾病活性中的作用
Isabel A Temperley1, Alexandra N Seldon1, Madeline Aw Reckord1
1School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Multiple sclerosis journal - experimental, translational and clinical
|December 22, 2023
概括
这项研究发现,两年来,乳制品或质摄入量与多发性硬化症 (MS) 疾病活动或生活质量之间没有联系. 可能需要对更大群体进行进一步的研究,以确认MS患者的这些发现.
科学领域:
- 神经学 神经学
- 饮食科学 饮食科学
- 免疫学 免疫学 免疫学
背景情况:
- 多发性硬化症 (MS) 管理通常涉及饮食建议,关于乳制品和质摄入量的建议各不相同.
- 关于乳制品和质对MS疾病活动的影响,存在相互矛盾的证据.
- 了解这些饮食关联对于基于证据的MS患者指导至关重要.
研究的目的:
- 研究乳制品和质消费与多发性硬化症患者的疾病活动之间的关联.
- 在两年时间内评估乳制品和质摄入量与生活质量之间的关系.
- 使用没有疾病活动证据 (NEDA) 3状态作为疾病活动的关键指标.
主要方法:
- 在两年内使用专门的饮食选器对186名多发性硬化症患者的乳制品和质摄入量进行了回顾性估计.
- 估计的饮食摄入量与没有疾病活性证据 (NEDA) 3状态的比较.
- 使用多发性硬化国际生活质量 (MusiQoL) 问卷评估生活质量.
主要成果:
- 在平均乳制品摄入量和NEDA 3状态 (p=0.15) 之间没有观察到统计学上显著的关联.
- 在平均质摄入量和NEDA 3状态 (p=0.60) 之间没有观察到统计学意义上的关联.
- 乳制品和质摄入量都没有与多发性硬化国际生活质量 (MusiQoL) 评分有显著的关系.
结论:
- 该研究没有发现乳制品或质摄入量与多发性硬化症疾病活动或生活质量之间存在显著的关联.
- 虽然由于研究的样本规模,不能完全排除适度的益处,但目前的发现表明没有直接联系.
- 需要对更大的队列进行进一步的研究,以确定乳制品和质在MS治疗中的作用.
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