NBER色图书数据集:一个用户指南
Maya Durvasula1, C Scott Hemphill2, Lisa Larrimore Ouellette3
1Department of Economics, Stanford University, United States of America.
Research policy
|December 22, 2023
概括
美国食品和药物管理局的色书的新开放版将批准的药物与专利和监管排他性联系起来. 该资源为药物研究提供了有价值的数据,尽管研究人员必须谨慎地使用它.
科学领域:
- 制药科学 制药科学
- 监管科学 监管科学
- 数据科学数据科学数据科学
背景情况:
- 美国食品和药物管理局 (FDA) 的色书是关键资源,将批准的药物与其专利和独家信息联系起来.
- 从历史上看,对这些数据的访问是有限的,这阻碍了对药物生命周期和市场排他性的全面研究.
研究的目的:
- 介绍FDA的色书的新数字化,开放式访问版本.
- 讨论使用这种增强数据集用于研究目的的实用性,机遇和挑战.
- 为了证明计算药物法律独家期限的用例.
主要方法:
- 美国食品和药物管理局的色书数据的数字化.
- 描述数据的覆盖范围,包括药物批准,专利和监管独家权.
- 对数据的完整性和准确性与行政数据集的实证验证.
主要成果:
- 现在可以获得"色书"的全面,开放式数字版本.
- 数据验证表明,药物专利独家关系的记录基本上是完整和准确的.
- 该资源有助于研究,例如计算药物法律独家期限.
结论:
- 数字化书为制药和监管科学研究人员提供了有价值的,可访问的资源.
- 了解和处理数据利用所需的选择是有效研究的关键.
- 这些开放访问的数据有可能大大推进关于药物排他性和市场动态的研究.
更多相关视频
08:22Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software
Published on: July 17, 2018
7.3K
09:10A Highly Scalable Approach to Perform Ecological Surveys of Selfing Caenorhabditis Nematodes
Published on: March 1, 2022
2.6K
相关概念视频
Biostatistics: Overview
246
Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...
Discrete variables are...
246
How Data are Classified: Numerical Data
28.6K
Data that are countable or measurable in specific units are called numerical or quantitative data. Quantitative data are always numbers. Quantitative data are the result of counting or measuring the attributes of a population. Amount of money, pulse rate, weight, number of people living in a town, and number of students who opt for statistics are examples of quantitative data.
Quantitative data may be either discrete or continuous. All quantitative data that take on only specific numerical...
Quantitative data may be either discrete or continuous. All quantitative data that take on only specific numerical...
28.6K
Statistical Analysis: Overview
6.6K
When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
6.6K
NMR Spectrometers: Overview
1.1K
NMR spectrometers consist of a strong magnet, a radiofrequency transmitter, and a detector attached to a computer console for recording spectra of samples containing NMR-active nuclei. In first-generation NMR instruments called continuous-wave spectrometers, the resonance frequencies of the nuclei are determined by frequency-sweep or field-sweep methods. The magnetic field strength is fixed and the rf signal is swept in the former, while the radiofrequency signal is fixed and the magnetic field...
1.1K
Introduction to Statistics
46.7K
The science of statistics involves collecting, analyzing, interpreting, and presenting data. The method of collecting, organizing, and summarizing data is called descriptive statistics. The systematic method of drawing inferences from the sample data and predicting unknown characteristics of a population is called inferential statistics.
In statistics, the collection of individuals or objects under study is called population. The idea of sampling is to select a portion of the larger population...
In statistics, the collection of individuals or objects under study is called population. The idea of sampling is to select a portion of the larger population...
46.7K
Nitric Oxide Signaling Pathway
5.0K
Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure...
5.0K
