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严重复发双边鼻的患者报告结果:心理测量评估和内容有效性

Adam Gater¹, Chloe Tolley¹, Rebecca Williams-Hall¹

¹Patient-Centered Outcomes, Adelphi Values Bollington Cheshire UK.

|December 22, 2023

概括

患者报告的结果测量,特别是视觉模拟尺度 (VAS),在临床试验中证明了评估严重的慢性鼻炎与鼻的症状的可靠性和有效性.

科学领域:

临床医学临床医学
耳鼻喉科耳鼻喉科耳鼻喉科
患者报告的结果

背景情况:

严重的慢性鼻炎 (CRS) 与复发的双边鼻 (NP) 缺乏药理治疗评估的特定患者报告的结果措施.
现有的措施可能无法完全捕捉患者在NP严重CRS的经验.

研究的目的:

评估视觉模拟尺度 (VAS) 对NP症状严重性的心理测量特性和内容有效性.
建立可靠的工具来评估严重CRS与NP的治疗效果.

主要方法:

使用临床试验数据进行回顾性心理测定验证 (二期梅波利祖马布研究).
针对内容有效性的横截面对患者进行定性采访 (认知总结).

主要成果:

个别的VAS项目显示可接受的可靠性,有效性和响应性,除了需要进一步评估的气味损失项目.
所有VAS项目都被患者理解得很好,相关,并被一致解释,证实了内容的有效性.

结论:

症状VAS措施在临床试验中支持评估疾病经验和治疗效果,用于重复性双边NP的严重CRS.
这些经过验证的尺度可以提高对这种患者群体中药理干预措施的评估.

关键词:

慢性犀牛鼻炎慢性鼻炎疾病的严重程度.人们的生活质量.视觉模拟尺度是一个可视模拟尺度.

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