丸激素在跨性别男性中使用
1Department of Endocrinology, Diabetes and Metabolism, Northwell Health, New Hyde Park, New York, USA.
Transgender health
|December 22, 2023
概括
丸对于跨性别男性来说是有效的,维持激素水平,并实现像美诺雷亚这样的期望效果. 然而,观察到高率的多细胞血和颗粒挤出,需要谨慎使用.
科学领域:
- 内分泌学 在内分泌学.
- 跨性别者健康 跨性别者健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 对跨性别男性来说,丸激素治疗至关重要.
- 探索各种激素输送方法是必不可少的.
- 丸提供了一种长效的选择.
研究的目的:
- 为了评估丸在跨性别男性的疗效.
- 评估丸激素治疗的短期不良影响.
- 扩大跨性别男性的治疗选择.
主要方法:
- 对30名跨性别男性进行了回顾性研究.
- 开始的丸在每周期675-825毫克.
- 根据丸激素水平 (1-6个月后插入) 调整剂量.
主要成果:
- 药理动力学与 cisgender 男人相似.
- 治疗性水平 (300-800 ng/dL) 维持了大约4个月.
- 实现了100%的厌血和声音加深.
- 多细胞血症 (46.67%) 和颗粒挤出 (13.33%) 的高率.
- 血腫 (6.67%) 和細胞炎 (3.33%) 的發病率很低.
结论:
- 丸是跨性别男性的可行的替代品.
- 对于患有多细胞血症或血栓栓塞风险的患者,建议谨慎.
- 需要进一步监测诸如多细胞血症之类的不良事件.
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