相关实验视频
Updated: Jul 7, 2025

06:22
Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
Published on: November 29, 2024
618
在2型糖尿病患者中,睡眠时间与左心室缩之间的关联
Lin Mu1,2, Chao Li3, Wenying Zhao1,2
1Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Beijing 101149, China.
International journal of endocrinology
|December 22, 2023
概括
睡眠时间较长,特别是超过8小时,与2型糖尿病 (T2DM) 患者的左心室缩 (LVH) 有关. 这一发现强调了睡眠时间作为管理T2DM中LVH风险的潜在因素.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 睡眠医学 睡眠医学
背景情况:
- 左心室缩 (LVH) 是2型糖尿病 (T2DM) 的重要并发症.
- 了解T2DM中LVH的风险因素对于患者管理至关重要.
研究的目的:
- 调查T2DM患者的睡眠时间和LVH患病率之间的关联.
- 确定与增加LVH风险相关的具体睡眠持续时间值.
主要方法:
- 对连续T2DM患者进行跨胸腔心声扫描 (TTE) 的分析.
- 使用单变量和多变量逻辑回归,包括受限立方线 (RCS) 模型.
- 包括2689名成年T2DM患者,提供睡眠时间和LVH状态的数据.
主要成果:
- 在2689名T2DM患者中,LVH被诊断为24.4%.
- 睡眠时间,BMI,Hb,BUN和HDL-c与LVH相关.
- 每天睡眠时间超过8小时与LVH独立相关.
结论:
- 长时间睡眠时间 (>8小时) 是T2DM患者LVH的独立风险因素.
- 血红蛋白,BUN和HDL-c也显示出与LVH的独立关联.
- 在临床评估和治疗2型糖尿病患有 LVH 风险的患者时,应考虑睡眠时间.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.4K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.4K
Diabetes: Symptoms, Diagnosis, and Complications
553
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
553
Insufficient Sleep and Sleep Deprivation
146
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
146
Carbohydrate Metabolism
11.2K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.2K
Diabetes Mellitus: Overview and Type I Subtype
2.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.7K

