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Updated: Jul 7, 2025

Characterization of pH-Dependent Reversible Self-Assembly of Amyloid Beta 1-40-Coated Gold Colloids
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Published on: March 21, 2025

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一种由由Aβ衍生而来的β-hairpin形成的β-桶状四聚体

Tuan D Samdin1, Chelsea R Jones1, Gretchen Guaglianone1

  • 1Department of Chemistry, University of California Irvine California 92697-2025 USA jsnowick@uci.edu.

Chemical science
|December 22, 2023
PubMed
概括

研究人员设计了β-粉样蛋白 (Aβ) β-hairpin,以模拟Aβ寡合体. 这些酸形成了稳定的四聚体和八聚体,表现出破坏膜和亡性质,为Aβ提供了对Aβ的洞察力.

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