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Updated: Jul 7, 2025

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells
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Published on: January 12, 2020

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SARS-CoV-2 NSP14 MTase活性对于诱导正规NF-κB激活至关重要

Marie J Tofaute1, Benjamin Weller2, Carina Graß1

  • 1Research Unit Signaling and Translation, Group Signaling and Immunity, Molecular Targets and Therapeutics Center, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.

Bioscience reports
|December 22, 2023
PubMed
概括

SARS-CoV-2 NSP14蛋白激活NF-κB信号,这是COVID-19高炎症的一个关键驱动因素. 它的甲基转移酶活性由NSP10和SAM稳定,对这种免疫反应至关重要.

关键词:
主体-病原体相互作用甲基转移酶是一种甲基转移酶.核因子是kappaBBB的核因子.

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