COVID-19感染与流产之间的关联,我们真正知道什么?
Ioannis Chrysanthopoulos1, Anastasios Potiris2, Eirini Drakaki1
1First Department of Obstetrics and Gynecology, Alexandra Hospital, Medical School, National and Kapodistrian University of Athens, 115 28 Athens, Greece.
Diseases (Basel, Switzerland)
|December 22, 2023
概括
在COVID-19感染的过程中,
科学领域:
- 生殖健康 生殖健康
- 传染性疾病 传染性疾病
- 产科 产科 产科 产科 产科
背景情况:
- 随着COVID-19的流行,人们对其对怀孕结果的影响产生了担忧.
- 血管激素转化酶2 (ACE2) 受体与SARS-CoV-2细胞进入有关,并在生殖生理学中发挥作用.
- 现有研究提出了关于COVID-19和早期怀孕流产之间的关联的相互矛盾的证据.
研究的目的:
- 为了调查COVID-19感染对流产发生率的影响.
- 为了确定潜在的病理生理机制,将COVID-19与早期妊娠损失联系起来.
主要方法:
- 在多个科学数据库中进行了全面的文献审查.
- 搜索涵盖了2020年1月至2023年8月期间发表的文章.
- 32篇相关文章从一组最初的364项已识别的研究中被选中.
主要成果:
- 一些案例研究表明,COVID-19和早期怀孕流产之间存在联系.
- 然而,大多数系统性审查和元分析表明,感染者与非感染者之间的流产率没有显著差异.
- 病例报告还提到COVID-19和第二个月末堕胎之间的关联.
结论:
- 进一步的研究至关重要,以了解与持续的全球COVID-19循环相关的生殖风险.
- 需要更大,更均和受控的研究来产生可靠的数据.
- 需要对高质量的研究进行元分析,以澄清COVID-19和流产之间的关系.
更多相关视频
07:13Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
Published on: March 25, 2016
18.5K
08:50A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
3.8K
相关概念视频
Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Meiosis vs. Mitosis
56.1K
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
56.1K
Sexually Transmitted Infections
317
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
317
Viral Recombination
23.5K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.5K
CRISPR
51.4K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
51.4K
Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
