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Updated: Jul 7, 2025

Characterization of In Vitro Differentiation of Human Primary Keratinocytes by RNA-Seq Analysis
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解开转录组形状,表观遗传动力学和牛皮样角质细胞的形态变化:"了解与牛皮病变性表皮的相似性"

Ameneh Ghaffarinia1,2,3, Szilárd Póliska4, Ferhan Ayaydin5,6

  • 1HCEMM-USZ Skin Research Group, H-6720 Szeged, Hungary.

Cells
|December 22, 2023
PubMed
概括

牛皮的炎症会改变细胞形态和基因表达. 轻微的炎症令人惊的是,比严重的炎症更多地反映了牛皮的皮肤转录组,揭示了动态的表观遗传变化.

关键词:
5-基甲基细胞氨酸 (5-hmC)五甲基细胞素 (5-mC)通过DNA氧甲基化进行DNA氧甲基化.通过DNA甲基化.细胞因子细胞因子表观遗传调节剂 表观遗传调节剂这是一种炎症炎症炎症炎症.质细胞 (keratinocyte) 是一种细胞.牛皮是一种牛皮.转录组 (transcriptome) 是一个转录组.

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