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一种用于预测阻力突变逐步积累中最可能发生的进化轨迹的计算方法

Ruth Charlotte Eccleston1, Emilia Manko1, Susana Campino1

  • 1Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.

eLife
|December 22, 2023
PubMed
概括

像Plasmodium这样的病原体中的耐药性通过突变进化,而表皮病则影响耐药性途径. 结合 afinity 准确地预测了抗性和突变顺序,与突变频率数据保持一致.

关键词:
在P. falciparum的研究中.在P.vivax中使用.抗微生物耐药性 抗微生物耐药性史诗主义就是一种史诗主义.进化生物学是进化的生物学.传染病是一种传染性疾病.微生物学的微生物.病原体的进化 病原体的进化

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