植物转移的介绍 对于初学者来说注释
1Small Grains and Potato Germplasm Research Unit, USDA-ARS, Aberdeen, ID 83210, USA.
Biology
|December 22, 2023
概括
本文简化了植物转位子注释的初学者,详细介绍了检测方法和分类挑战. 它旨在提高植物基因组中移动DNA序列识别的准确性.
科学领域:
- 基因组学就是基因组学.
- 分子生物学分子生物学
- 生物信息学是一种生物信息学.
背景情况:
- 转子体,移动DNA序列,对植物基因组大小和进化有显著的贡献.
- 准确的转位子注释对于理解基因组动力学和开发分子工具至关重要.
- 植物基因组的复杂性和转子子进化对准确的注释和发现提出了挑战.
研究的目的:
- 为初学者提供植物转位子注释的指南.
- 总结当前的转子子检测策略和植物中的超级家族.
- 讨论转位子分类,错误注释识别和数据库质量改进.
主要方法:
- 基于重复,基于结构和基于同质性的转子子检测策略的审查.
- 已识别的植物转位子超级家族的汇编.
- 讨论植物转子子子检测的生物信息学资源.
主要成果:
- 三种主要的转位子注释方法的概述.
- 介绍已知的植物转位子超级家族和相关的生物信息学工具.
- 解释将转位子分类为"自主"或"非自主"的限制.
结论:
- 准确的转位子注释需要生物学和生物信息学方面的专业知识.
- 本综述提供了关于识别和纠正错误注释转位的指导.
- 改进的转子子数据库对于推进植物基因组学研究至关重要.
更多相关视频
相关概念视频
Overview of Transposition and Recombination
15.5K
Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
15.5K
DNA-only Transposons
14.5K
DNA-only transposons are called autonomous transposons since they code for the enzyme transposase that is required for the transposition mechanism. Insertion of transposons can alter gene functions in multiple ways. They can mutate the gene, alter gene expression by introducing a novel promoter or insulator sequence, introduce new splice sites, and change the mRNA transcripts produced, or remodel chromatin structure.
The donor site from where the transposon is excised is either degraded or...
The donor site from where the transposon is excised is either degraded or...
14.5K
LTR Retrotransposons
17.5K
LTR retrotransposons are class I transposable elements with long terminal repeats flanking an internal coding region. These elements are less abundant in mammals compared to other class I transposable elements. About 8 percent of human genomic DNA comprises LTR retrotransposons. Some of the common examples of LTR retrotransposons are Ty elements in yeast and Copia elements in Drosophila.
The internal coding region of LTR retrotransposons and their mechanism of transposition closely resembles a...
The internal coding region of LTR retrotransposons and their mechanism of transposition closely resembles a...
17.5K
Transgenic Plants
7.2K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.2K
Non-LTR Retrotransposons
11.5K
As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
11.5K
Transgenic Organisms
31.2K
Overview
31.2K


